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In this series, the only prognostic factor for patients with advanced-stage borderline tumor is the type of peritoneal implant. More patients died of the treatments complications than of the disease itself.
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In a trial that included androgen-independent prostate cancer patients, 2 drug regimens were shown by randomized phase II analysis to be comparable. Both produced survival advantage when compared to prior series, including those in which mitoxantrone and prednisone were used.
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Participants in the initial Multicenter Study of Hydroxyurea in Sickle Cell Anemia interventional trial were followed, upon completion of that trial for up to 9 years, to determine the long-term effects of treatment. In this publication of the observational phase of the MSH trial, there is noted a 40% reduction in mortality for those who had received a year or more of the drug.
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Women with advanced epithelial ovarian cancer did not describe the treatment decision-making process as shared; rather, they described an interaction that was directed by their physician.
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There are no well-defined guidelines for the treatment of primary cutaneous B-cell lymphoma (PCBCL). Since it is an uncommon diagnosis, it is unlikely that answers will come from randomized trials. This retrospective study from 2 German centers evaluated outcomes from a cohort of 35 patients and concluded that radiotherapy to all visible lesions is the treatment of choice.
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Detection of Alzheimers Disease and Dementia in the Preclinical Phase; Shoe Design and Plantar Pressures in Neuropathic Feet; Serum Thyroid Stimulating Hormone in Assessment of Severity of Tissue Hypothyroidism in Patients with Overt Primary Thyroid Failure.
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A high intake of nondairy protein may accelerate renal function decline in women with mild renal insufficiency.
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Adding continuous positive airway pressure (CPAP) to medical therapy in patients who have obstructive sleep apnea and congestive heart failure both improves systolic function and lowers blood pressure.
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Keeping the INR in the range of 1.5 to 2.0 is safe and effective.